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Illinois “Nightmare Bacteria” Outbreak Raises Alarms

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January 8, 2014, 2:59 pm ET

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The largest U.S. outbreak on record of one particular strain of a so-called “nightmare bacteria” is fueling alarm among public health officials about the spread of potentially lethal drug-resistant infections.

The outbreak, which has been traced to Advocate Lutheran General Hospital in suburban Chicago, has so far infected 44 people, according to the Centers for Disease Control and Prevention. Since 2009, just 97 cases of the infection have been reported to the agency.

The bacteria strain, known as carbapenem-resistant enterobacteriaceae (CRE), is a form of superbug that lives in the gut and can carry a gene called NDM-1 that is resistant to practically all antibiotics on the market today. Perhaps more alarming, the gene can jump from bacteria to bacteria, making treatable infections untreatable.

Before the Illinois outbreak, the largest spread of CRE that officials had seen was eight cases at a Denver hospital in 2012. When signs of the infection surfaced in Illinois, officials contacted 243 patients they believed came into contact with the bug during an endoscopic procedure. Of the 114 who returned for testing, 28 screened positive as carriers but did not have any symptoms. Ten others showed symptoms. The CDC also found six additional cases at a separate Illinois facility.

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